In the world of software systems, PioneerRx is one of the top-selling solutions: but is it the right fit for you?

As you start your search for a new pharmacy management system, it’s important that you get the facts, read the reviews, and weigh your options appropriately.

To aid you in this effort, we’ve compiled everything you need to know about PioneerRx Pharmacy Software

Read on to learn all about PioneerRx, from its founders to its features to how it’s rated among pharmacists — and find out if this system is the right pick for your business. 

What is PioneerRx?

PioneerRx Pharmacy Software is one of the newest systems on the market, but it has quickly risen to the top.

PioneerRx got its start in 2008 in small-town Shreveport, Louisiana. In a little over 10 years, it’s expanded to 47 states and operated in 5,000 independent pharmacies. PioneerRx’s growth has only accelerated after it was acquired by RedSail Technologies in late 2020.

PioneerRx is currently headquartered in Irving, TX under the leadership of President Jeff Key. Then and now, though, PioneerRx’s mission is to Save + Revitalize Independent Pharmacy. This is accomplished through software solutions, outreach efforts, and side projects, like PioneerRx’s Catalyst Pharmacy Podcast.

PioneerRx currently offers its flagship pharmacy management system, along with a variety of mobile apps, add-ons, and integrations designed to supplement the system.

What are the features of PioneerRx?

PioneerRx offers a number of features in its flagship pharmacy management system. These features can be broken down into the following categories:

MTM / Adherence

  • Med Sync
  • Patient Risk Score
  • Five Star Reporting and Improvement
  • Automatic Refill
  • Patient Labs
  • Patient Engagement
  • OutcomesMTM Integration

Enhanced Workflow

  • Interactive Voice Response (IVR)
  • Document Management
  • Intake Station
  • Pre-Check Station
  • Bulk Patient Process
  • Customizable Workflow
  • Driver’s License Scanning
  • Prescriber and Insurance Lookup
  • Will Call Bin Management
  • Automatic COB Billing
  • Employee Time Clock
  • Premade & Custom Signs
  • To-Do List
  • Cloud Fax
  • CoverMyMeds Integration

Inventory & Ordering

  • Usage-Based Ordering
  • Drug Loan Tracking
  • Multiple Wholesaler Ordering
  • Automatic Reorder Points
  • Recommended Ordering and Returns
  • Multiple Inventories
  • Shelf Stickers

Finance & Reporting

  • Accounts Receivable
  • Third-Party Reconciliation
  • DIR Fee Management
  • Pre- and Post-Edits
  • Claim Overrides
  • Competitive Pricing
  • AWP Rebilling Service
  • Customized Searching and Reporting
  • Drug Manufacturer Reporting
  • Export to Excel / PDF

Integrated Point-of-Sale

  • Touch Screen
  • Real-Time Prescription Status
  • PSE Tracking
  • Gift Cards
  • Apply Pay
  • Loyalty Program
  • VIP Patient Rankings
  • Credit Card Autopay
  • End-to-End Encryption
  • Delivery Management
  • Bundle Rx and OTCs


  • Scales
  • Batches
  • Multi-Batch Compounding
  • Recommended Pricing
  • Compound Billing

Long Term Care / Facility

  • MARs and Physician Orders
  • Cycle Fill
  • Facility Billing

Security & Support

Mobile Apps & Add-Ons

In addition to the pharmacy management system, PioneerRx offers several mobile apps and add-ons that can be purchased for an additional fee. These include the:

  • RxLocal Mobile App
  • Drive-Thru App
  • Delivery App
  • Inventory App
  • Patient Counseling App
  • Cloud Fax Add-On


Supplementing apps and add-ons, PioneerRx also offers an assortment of integrations to add to your standard software system. For a full list of integrations from PioneerRx, click here.

To learn more about each of PioneerRx’s features, visit the company website.

How much does PioneerRx cost?

Like most software systems, PioneerRx doesn’t take a one-size-fits-all approach to pricing. Your final price depends on your unique needs: the prescriptions you fill, the patients you have, and the services you perform. To get more general information about software system pricing, look to our blog.

For PioneerRx pricing in particular, click to schedule a demo and get a personalized quote for your pharmacy.

Is PioneerRx a good software system?

PioneerRx is one of the top-selling pharmacy software systems on the market. According to a 2021 Direct Opinions survey of over 2,000 independent pharmacists, PioneerRx performs consistently across several categories. Compared to other software systems, PioneerRx typically ranks at the top.

In this most recent survey, PioneerRx scored in the following categories:

These results indicate that most pharmacists are satisfied with their PioneerRx pharmacy software system.

For a full breakdown of the Direct Opinions survey results, and to see how PioneerRx stacks up against the competition, visit our Compare Software page.

Who are PioneerRx’s competitors?

The top 8 software systems competing against PioneerRx include:

To learn more about each of PioneerRx’s competitors, and to see how they stack up, visit our blog, What Are the Best Pharmacy Software Systems on the Market?

How can I learn more about PioneerRx?

If you’re looking to learn more, request a demo with a PioneerRx representative. In your demo, a representative will explain the software to you, answer your specific questions, and help you decide if the software will be a good fit for your pharmacy.

When you do decide to schedule our demo, make sure that you ask these 10 questions in order to make the most informed decision.


PioneerRx is one of the most popular pharmacy management systems on the market right now, and it might make a good fit for you. Take some time to consider what you want out of your pharmacy management system, then consider the features and functionalities that come alongside PioneerRx.

Schedule a demo, talk to a representative, and feel good about making an educated decision with your pharmacy software system. It’s the most important decision you’ll make as a pharmacy owner — so don’t take it lightly.